49ers' Stunning Upset Has NFL Fans Screaming: What Went Wrong in San Francisco?

The San Francisco 49ers suffered a devastating loss at the hands of the Arizona Cardinals on Sunday, falling to a disappointing 2-3 record in the process. The 49ers, who were heavily favored to win at home, were left stunned and searching for answers after the 31-28 defeat.

The loss was a crushing blow to the 49ers' playoff hopes, and now they face an even tougher challenge as they prepare to take on the Seattle Seahawks on Thursday Night Football. The Seahawks, who are currently riding a two-game winning streak, will be looking to hand the 49ers their third consecutive loss and further derail their season.

So, what went wrong for the 49ers on Sunday? The answer is simple: turnovers and poor defense. The 49ers turned the ball over three times, including two costly fumbles that led to Cardinals touchdowns. Meanwhile, the defense was unable to contain Cardinals quarterback Kyler Murray, who threw for 210 yards and a touchdown while also rushing for 29 yards.

"We just didn't play well enough to win," 49ers head coach Kyle Shanahan said after the game. "We had too many turnovers and didn't make enough plays on defense. We have to be better than that if we want to win in this league."

The 49ers' loss was also marred by injuries, as several key players were forced to leave the game due to various ailments. The 49ers are already dealing with a plethora of injuries, and the loss of any more players could be catastrophic to their season.

Looking ahead to Thursday night, the 49ers will need to regroup and refocus if they hope to come away with a win. They will need to limit their turnovers and find a way to contain the Seahawks' high-powered offense, led by quarterback Russell Wilson. It won't be an easy task, but the 49ers are confident that they can bounce back from their disappointing loss.

"We're not giving up," 49ers quarterback Jimmy Garoppolo said. "We're going to keep fighting and try to get back on track. We have a tough game ahead of us on Thursday, but we're ready for the challenge."